Use of DOACs anticoagulants in patients with Antithrombin III deficiency

Dr. Dana Shani Back to your profile PDF Version Research Inquiry Can she be safely switched to DOACS? Patient’s Summary 40 years old WF, bx of massive PE, found to have AT III deficiency and has been on Coumadin for 15 years.  Conclusion While researching this inquiry, we found little high-quality data (RCTs, Meta-analysis) describing […]

Concomitant use of TKI sand Radiation therapy

Dr. Dana Shani Back to your profile PDF Version Research Inquiry A 78 years old white male, with a history of CML currently on Dasatinib, developed Prostate cancer and is in need of local radiation to the prostate.  This summarized report will review and present information regarding the safety of possible treatments using Dasatinib or […]

Hype viscosity & elevated serum antibodies titers – surgical safety

Dr. Dana Shani Hype viscosity & elevated serum antibodies titers – surgical safety Back to your profile PDF Version Research Inquiry 70 y/o male was found to have prolonged PTT prior to surgery…work up revealed elevated titers of lupus anticoagulants and anticardiolipin antibodies and elevated IgM 3225 (norm 35-242) with elevated serum viscosity of 2.6 […]

Professor Amir On

Lung Adenocarcinoma Possible Treatments | 04.07.22 Research Inquiry Which treatment option may be considered for a 72 years old male with pulmonary adenocarcinoma with pleural effusion containing malignant cells that harbored mutations in exon 21 L858R and exon 18 L718Q and with high PD-L1 expression, that was treated and progressed on Gefitinib, Osimertinib, and Carboplatin-Pemetrexed-Pembrolizumab? […]

PAN & SAM comparison

Dr. Kai Sun Polyarteritis Nodosa & Segmental Arterial Mediolysis comparison | 12.08.22 (Download PDF) Research Inquiry Are there any distinguishing features between polyarteritis nodosum (PAN) and segmental arterial mediolysis (SAM) in terms of clinical course, laboratory, and radiographic findings, when a biopsy can not be performed? Conclusion According to the research findings there are some […]

Sample Research – CAR T-Cells Therapy in T-cell ALL

CAR T-Cells Therapy in T-cell ALL |  09.08.22 [View as PDF] Conclusion According to our review of the latest clinical trials and literature, although CAR T-cell treatment has promising in vivo and in vitro results, using it for T-ALL first relapse is debatable, considering the lack of phase II clinical trial efficacy data, risk of […]

Sample Research – Neuroblastoma first-line treatment safety

Neuroblastoma first-line treatment safety |  09.08.22 [View as PDF]   Research Inquiry 1.1 years old patient with a recent diagnosis of inoperable Neuroblastoma in the left adrenal gland, INRGSS Stage L2, and Opsoclonus-myoclonus syndrome with rapid eye movements and potential decreased visual acuity. Her OMS is treated with dexamethasone PO 20mg/m2/day. The following protocols were […]

Prof. Ronni Gamzu

Pediatric Hemato-oncology Medical Researches Neuroblastoma first-line treatment safety     [PDF] CAR T-Cells Therapy in T-cell ALL    [PDF] Contact us USA: +1 628 227 0024 ISL: +972 3 309 4421 Email:

Hereditary Hemorrhagic Telangiectasia & Surgical Bleeding | 29.07.22 Research Inquiry 26 years old white female, history of Hereditary Hemorrhagic Telangiectasia (Osler -Weber -Randu), made by ears, nose and throat physician, but no genetic confirmation. History of multiple nose bleeds, but no Iron Deficiency Anemia (IDA), and normal coags. The patient had a traumatic ankle fracture, […]

Dr. Bella Mehta

Zoster vaccine Dr. Bella Mehta View as PDF Research Inquiry Protocols for the use of Zoster vaccines in patients with rheumatoid arthritis, timing, vaccination options and contraindications regarding JAK inhibitors and bDMARDS. Conclusion Vaccination with the non-live vaccine (Shingrix) is generally preferable in RA patients. live-attenuated or live vaccines are not recommended during treatment and […]